Effects of high-intensity interval training on patients with type 2 diabetes mellitus A narrative review

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Alberto Kramer Ramos
Antelm Pujol Calafat
Pablo Jiménez Martínez
Carlos Alix Fages


Diabetes Mellitus (DM) which is characterized by pancreatic beta-cell dysfunction, peripheral insulin resistance, or both, is one of the most relevant cardiovascular risk factors worldwide. Its most prevalent and studied form is type 2 diabetes mellitus (DM2), a chronic multifunctional condition linked to physical inactivity and lifestyle. The purpose of this narrative review is to explore the implications of high intensity interval training on different hemodynamic, biochemical and anthropometric parameters of DM2 patients. Findings yielded that high-intensity interval training is a safe and recommended training method to improve functional capacity and certain parameters such as body weight and body mass index (BMI), systolic blood pressure (SBP), VO2 maximum (peak) and Hb1Ac, compared to moderate and low intensity training, and passive controls. Moreover, the benefits of physical exercise are independent of weight loss and there is no nutritional protocol or drug to replace them.

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How to Cite
Kramer Ramos, A., Pujol Calafat, A., Jiménez Martínez, P., & Alix Fages, C. (2022). Effects of high-intensity interval training on patients with type 2 diabetes mellitus: A narrative review. Scientific Journal of Sport and Performance, 2(1), 36–43. https://doi.org/10.55860/STBC2316
Review Paper
Author Biographies

Alberto Kramer Ramos, Reina Sofia Hospital

Specialist Doctor in Family and Community Medicine.

Antelm Pujol Calafat, Son Llátzer Hospital

Resident Doctor of Endocrinology and Nutrition.

Pablo Jiménez Martínez, University of Valencia

Research Group in Prevention and Health in Exercise and Sport (PHES).

Carlos Alix Fages, Autonomous University of Madrid

Applied Biomechanics and Sport Technology Research Group.


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